Hepatic effects of phenobarbital

Environmental Health laboratory of Sumitomo Chemical Company (Japan) published a paper “Comparison of the hepatic effects of phenobarbital in chimeric mice containing either rat or human hepatocytes with humanized…

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Hepatic effects of phenobarbital
Hepatic effects of phenobarbital in PXB-mouse

Mitochondrial toxicity in PXB-cells®

Mitochondrial toxicity is one of the pathogenic mechanisms of severe drug-induced liver injury (DILI). It is desirable to identify severe DILI risks early in development, however it is extremely…

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Mitochondrial toxicity in PXB-cells®
Mitochondria toxicity assessment with PXB-cells and Cryopreserved Human Hepatocytes