Hepatic effects of phenobarbital

 Environmental Health laboratory of Sumitomo Chemical Company (Japan) published a paper “Comparison of the hepatic effects of phenobarbital in chimeric mice containing either rat or human hepatocytes with humanized…

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Hepatic effects of phenobarbital in PXB-mouse

Mitochondrial toxicity in PXB-cells®

Mitochondrial toxicity is one of the pathogenic mechanisms of severe drug-induced liver injury (DILI). It is desirable to identify severe DILI risks early in development, however it is extremely…

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Mitochondria toxicity assessment with PXB-cells and Cryopreserved Human Hepatocytes

Fresh human hepatocytes for your research

PXB-cells® applications https://www.youtube.com/watch?v=uxGxs1nKoHE PXB-cells® are fresh human hepatocytes isolated from the PXB-mouse®. We offer consistent delivery on your schedule and from the same donor source. PXB-cells® are useful in…

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Use of PXB-cells in DMPK-Toxicity, Hepatitis Studies, NASH-NAFLD, Gene Editing

International NASH Day 2020

 International NASH Day - June 12 - is aimed to increase public awareness about non-alcoholic steatohepatitis (NASH). NASH is characterized by the presence of an abnormal accumulation of fat…

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NASH Day 2020

Species differences in liver accumulation and metabolism

 Species differences in liver accumulation and metabolism of nucleotide prodrug are discussed in the April 2020 publication by Gilead team.The difficulty in projecting human dose based on preclinical data…

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Gilead_Species differences in liver accumulation and metabolism of nucleotide prodrug_PXB-mouse and PXB-cells

COVID-19 Update from PhoenixBio Group

PhoenixBio's Response to COVID19 Dear Valued Customers, Collaborators and Partners,We are writing this letter to ensure you that the PhoenixBio Group continues to operate at full capacity and is…

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Covid-19 update - PhoenixBio