Hepatic effects of phenobarbital
Environmental Health laboratory of Sumitomo Chemical Company (Japan) published a paper “Comparison of the hepatic effects of phenobarbital in chimeric mice containing either rat or human hepatocytes with humanized…
Environmental Health laboratory of Sumitomo Chemical Company (Japan) published a paper “Comparison of the hepatic effects of phenobarbital in chimeric mice containing either rat or human hepatocytes with humanized…
We are excited to share the Takeda team’s study results generated with the support of PhoenixBio through the Chimeric Mouse with Humanized Liver (CMHL) Consortium. The paper titled “Prediction…
Mitochondrial toxicity is one of the pathogenic mechanisms of severe drug-induced liver injury (DILI). It is desirable to identify severe DILI risks early in development, however it is extremely…
PXB-cells® applications https://www.youtube.com/watch?v=uxGxs1nKoHE PXB-cells® are fresh human hepatocytes isolated from the PXB-mouse®. We offer consistent delivery on your schedule and from the same donor source. PXB-cells® are useful in…
International NASH Day - June 12 - is aimed to increase public awareness about non-alcoholic steatohepatitis (NASH). NASH is characterized by the presence of an abnormal accumulation of fat…
PXB-mouse® was used to assess glucuronide formation and pharmacokinetics in human hepatocytes in vivo, as published by Phenex Pharmaceuticals AG team in ACS Medicinal Chemistry Letters “Discovery of Hydroxyamidine…
During last two months many of us saw their colleagues only via such applications as Zoom, WebEx, Google Hangouts and other video conferencing systems. With conferences and workshops going…
Species differences in liver accumulation and metabolism of nucleotide prodrug are discussed in the April 2020 publication by Gilead team.The difficulty in projecting human dose based on preclinical data…
PhoenixBio's Response to COVID19 Dear Valued Customers, Collaborators and Partners,We are writing this letter to ensure you that the PhoenixBio Group continues to operate at full capacity and is…
PhoenixBio at 2020SOTPhoenixBio poster presentations and booth exhibition sponsorship were planned for the SOT 59th Annual Meeting and ToxExpo from March 15th – March 19th, 2020 in Anaheim, California,…