Chimeric Mouse Model with
Highly Humanized Liver
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KMT Hepatech, Inc. is a part of PhoenixBio group since December 1, 2017

KMT Hepatech is a production facility of PhoenixBio Group products (PXB-mouse® and PXB-cells®) in North America.
PhoenixBio Group is utilizing its proprietary platform technology of small animal model of chimeric mouse with highly humanized liver, the PXB-mouse®.

The PXB-mouse® and PXB-cells® are your essential tools for therapeutics and vaccine development.

PXB mouse

Mouse bulletCommercial scale production of high quality chimeric mice

Mouse bulletAlways available for shipment

Mouse bulletStable engraftment for entire lifespan

Mouse bulletLong-term  applications – over 30 days in study

Mouse bulletOn-demand supply with consistent donor for in vitro reproducibility

Mouse bulletCompatible with your preferred format including 3D

News and Events

Oligonucleotides and the humanized liver mouse model

Oligonucleotides remain compounds of high interest in drug development, especially with recent advancements in chemistry and delivery technologies. With more compounds progressing further in preclinical development, the need for physiologically…

Hepatic effects of phenobarbital

Environmental Health laboratory of Sumitomo Chemical Company (Japan) published a paper “Comparison of the hepatic effects of phenobarbital in chimeric mice containing either rat or human hepatocytes with humanized constitutive…

Mitochondrial toxicity in PXB-cells®

Mitochondrial toxicity is one of the pathogenic mechanisms of severe drug-induced liver injury (DILI). It is desirable to identify severe DILI risks early in development, however it is extremely difficult…